Material Safety Data Sheet

  BRICORR 50A

Date Prepared:  7/16/07

  Supersedes Date:  2/01/07

  1. PRODUCT AND COMPANY IDENTIFICATION

RHODIA INC.
RHODIA NOVECARE
CN7500
8 Cedar Brook Drive
Cranbury NJ 08512-7500

Emergency Phone Numbers:
FOR EMERGENCIES INVOLVING A SPILL, LEAK, FIRE, EXPOSURE OR ACCIDENT CONTACT: CHEMTREC (800-424-9300 within the United States or 703-527-3887 for international collect calls) or Rhodia CAERS (Communication and Emergency Response System) at 800-916-3232.

For Product Information:
(888) 776-7337

Chemical Name or Synonym:
TETRAKIS(HYDROXYMETHYL) PHOSPHONIUM SULFATE; THPS

Molecular Formula:
2(C4H12O4P).O4S


  2. HAZARDS IDENTIFICATION

A. EMERGENCY OVERVIEW:

Physical Appearance and Odor:
colorless to pale yellow / liquid, characteristic odor.

Warning Statements:
DANGER! RISK OF SERIOUS DAMAGE TO EYES. HARMFUL IF INHALED. HARMFUL IF SWALLOWED. MAY CAUSE ALLERGIC SKIN REACTION. POSSIBLE DEVELOPMENTAL HAZARD, MAY ADVERSELY EFFECT THE DEVELOPING FETUS (BASED ON ANIMAL DATA).

B. POTENTIAL HEALTH EFFECTS:

Acute Eye:
Expected to cause significant irritation to the eyes. May cause redness, burns, irritation, tearing.

Acute Skin:
May cause irritation upon prolonged contact. May cause redness, inflammation, May cause sensitization.

Acute Inhalation:
Harmful if inhaled. May cause coughing, respiratory tract irritation, shortness of breath.

Acute Ingestion:
Harmful if ingested. May cause nausea, vomiting.

Chronic Effects:
Repeated, prolonged ingestion may cause liver damage, (See Section 11-Chronic for a discussion of animal studies.) In a rabbit study, animals fed this product during pregnancy produced an increase in the numbers of offspring with eye abnormalities and/or minor skeletal variations, only at doses that also caused maternal (parental) toxicity. (See Section 11 for details of chronic studies).


  3. COMPOSITION/INFORMATION ON INGREDIENTS

Component CAS Reg Number OSHA
Hazard		 % WT/WT
TETRAKIS(HYDROXYMETHYL) PHOSPHONIUM SULFATE 55566-30-8 Y ~ - 50


  4. FIRST AID MEASURES

FIRST AID MEASURES FOR ACCIDENTAL:

Eye Exposure:
Hold eyelids open and flush with a steady, gentle stream of water for at least 15 minutes. Seek immediate medical attention.

Skin Exposure:
In case of contact, immediately wash with plenty of soap and water for at least 5 minutes. Seek medical attention if irritation developes or persists. Remove contaminated clothing and shoes. Clean contaminated clothing and shoes before re-use.

Inhalation:
Remove victim from immediate source of exposure and assure that the victim is breathing. If breathing is difficult, administer oxygen, if available. If victim is not breathing, administer CPR (cardio-pulmonary resuscitation). Seek medical attention.

Ingestion:
Wash out mouth with water and keep at rest. Seek immediate medical attention.

MEDICAL CONDITIONS POSSIBLY AGGRAVATED BY EXPOSURE:
Skin contact may aggravate existing skin disease.

NOTES TO PHYSICIAN:
All treatments should be based on observed signs and symptoms of distress in the patient. Consideration should be given to the possibility that overexposure to materials other than this product may have occurred.

Treat symptomatically. No specific antidote available.


  5. FIRE FIGHTING MEASURES

FIRE HAZARD DATA:

Flash Point:
Not Applicable

Extinguishing Media:
Recommended: water fog, carbon dioxide, dry chemical, foam.

Special Fire Fighting Procedures:
Firefighters should wear NIOSH/MSHA approved self-contained breathing apparatus and full protective clothing. Keep unnecessary people away, isolate hazard area and deny entry. Stay upwind; keep out of low areas. Evacuate residents who are downwind of fire.

Unusual Fire and Explosion Hazards:
Containers may explode (due to the build-up of pressure) when exposed to extreme heat.

Hazardous Decomposition Materials (Under Fire Conditions):
oxides of sulfur
oxides of phosphorus
oxides of carbon


  6. ACCIDENTAL RELEASE MEASURES

Evacuation Procedures and Safety:
Ventilate closed spaces before entering. Personnel handling this material should be thoroughly trained to handle spills and releases. Wear appropriate protective gear for the situation. See Personal Protection information in Section 8. Evacuate and isolate spill area.

Containment of Spill:
Stop leak if it can be done without risk. Dike spill using absorbent or impervious materials such as earth, sand or clay. Dike area to prevent runoff. Collect and contain contaminated absorbent and dike material for disposal.

Cleanup and Disposal of Spill:
Recover material, if possible. DO NOT RETURN MATERIAL TO ITS ORIGINAL CONTAINER. Absorb with an inert absorbent. Shovel up into an appropriate closed container (see Section 7: Handling and Storage). The material should be properly packaged and disposed of in compliance with applicable regulations. Clean up residual material by washing area with water. Collect washings for disposal. Decontaminate tools and equipment following cleanup.

Environmental and Regulatory Reporting:
Do not flush to drain. Runoff from fire control or dilution water may cause pollution. Prevent material from entering public sewer system or any waterways. Spills may be reportable to the National Response Center (800-424-8802) and to state and/or local agencies.


  7. HANDLING AND STORAGE

Minimum/Maximum Storage Temperatures:
Not Available

Handling:
Personnel handling this product should be thoroughly trained as to its hazards. Do not get on skin or in eyes. Do not breathe vapors and mists. Use only as directed.

** HAZARD WARNING: This product belongs to a chemical family that HAS BEEN TESTED in combination with Trimethylolpropane , Trimethylolpropane derived products or their corresponding Trimethylolpropane homologs for toxicity of the thermal decomposition products in the absence of flame. Products in this chemical family PRODUCED NO SIGNIFICANT ADVERSE HEALTH EFFECTS in laboratory animals. However, there is a possibility that this thermal decomposition may produce bicyclic phosphates and/or phosphites in combination with certain other phosphorus compounds. Bicyclic phosphates and phosphites have acute neurotoxic properties and may cause convulsive seizures in laboratory test animals. Follow all precautionary measures outlined in this Material Safety Data Sheet and/or contact Rhodia Inc.

Storage:
Store in an area that is clean, cool, dry, well-ventilated, Store away from; bases, oxidizers, reducing agents, Store in tightly closed containers. Container material to avoid: ordinary steel, Recommended container material: high density, high molecular weight polyethylene containers.


  8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Introductory Remarks:
These recommendations provide general guidance for handling this product. Because specific work environments and material handling practices vary, safety procedures should be developed for each intended application. While developing safe handling procedures, do not overlook the need to clean equipment and piping systems for maintenance and repairs. Waste resulting from these procedures should be handled in accordance with Section 13: Disposal Considerations.

Assistance with selection, use and maintenance of worker protection equipment is generally available from equipment manufacturers.

Exposure Guidelines:
Exposure limits represent regulated or recommended worker breathing zone concentrations measured by validated sampling and analytical methods, meeting the regulatory requirements. The following limits apply to this material, where, if indicated, S=skin and C=ceiling limit:

TETRAKIS(HYDROXYMETHYL) PHOSPHONIUM SULFATE
  Notes TWA STEL
ACGIH 2 mg/cu m

Engineering Controls:
Where engineering controls are indicated by use conditions or a potential for excessive exposure exists, the following traditional exposure control techniques may be used to effectively minimize employee exposures: general area dilution/exhaust ventilation.

Respiratory Protection:
When respirators are required, select NIOSH/MSHA approved equipment based on actual or potential airborne concentrations and in accordance with the appropriate regulatory standards and/or industrial recommendations.

Eye/Face Protection:
Eye and face protection requirements will vary dependent upon work environment conditions and material handling practices. Appropriate ANSI Z87 approved equipment should be selected for the particular use intended for this material.

Eye contact should be prevented through use of chemical safety glasses with side shields or splash proof goggles. An emergency eye wash must be readily accessible to the work area. Face contact should be prevented through use of a face shield.

Skin Protection:
Skin contact should be prevented through use of suitable protective clothing, gloves and footwear, selected with regard for use conditions and exposure potential. Consideration must be given both to durability as well as permeation resistance.

Work Practice Controls:
Personal hygiene is an important work practice exposure control measure and the following general measures should be taken when working with or handling this material:
(1) Do not store, use, and/or consume foods, beverages, tobacco products, or cosmetics in areas where this material is stored.
(2) Wash hands and face carefully before eating, drinking, using tobacco, applying cosmetics, or using the toilet.
(3) Wash exposed skin promptly to remove accidental splashes or contact with this material.


  9. PHYSICAL AND CHEMICAL PROPERTIES

Physical and Chemical properties here represent typical properties of this product. Contact the business area using the Product Information phone number in Section 1 for its exact specifications.

Physical Appearance:
colorless to pale yellow / liquid.

Odor:
characteristic odor.

pH:
3 to 6 at 100 wt/wt%.

Specific Gravity:
1.24 at 20 C (68 F).

Density:
1.22 to 1.26 g/ml at 20 C (68 F).

Water Solubility:
miscible

Melting Point Range:
Not Available

Freezing Point Range:
~ -10 C (14 F)

Boiling Point Range:
Not Available

Vapor Pressure:
Not Available

Vapor Density:
Not Available

Molecular Weight:
406.3


  10. STABILITY AND REACTIVITY

Chemical Stability:
This material is stable under normal handling and storage conditions described in Section 7. Under unusual conditions, such as very high temperatures and/or in the presence of strong reducing agents, the product may break down to form hazardous decomposition products noted below. The customer is advised to seek further advice from Rhodia Water Technical Service personnel when considering such applications.

Conditions To Be Avoided:
heat
Temperatures above 160C.
See HAZARD WARNING under HANDLING : in Section 7.

Materials/Chemicals To Be Avoided:
strong bases
strong acids
strong oxidizing agents
strong reducing agents

Decomposition Temperature Range:
> 160 C (320 F)

The Following Hazardous Decomposition Products Might Be Expected:

Decomposition Type: thermal
oxides of sulfur
oxides of phosphorus
oxides of carbon
phosphine gas

Hazardous Polymerization Will Not Occur.

Avoid The Following To Inhibit Hazardous Polymerization:
not applicable


  11. TOXICOLOGICAL INFORMATION

Acute Eye Irritation:
The following data are for similar or related products.
  Toxicological Information and Interpretation:
  eye - eye irritation, rabbit. Severely irritating. This material is expected to cause significant irritation to the eyes.

Acute Skin Irritation:
The following data is for similar or related products.
  Toxicological Information and Interpretation:
  skin - skin irritation, rabbit. This material is not expected to cause significant irritation to the skin.
  skin - sensitization, guinea pig. Sensitizing. May cause significant allergic skin reaction. Material tested was a 75% aqueous solution of Tetrakis (hydroxymethyl) phosphonium sulfate.

Acute Dermal Toxicity:
The following data is for similar or related products.
  Toxicological Information and Interpretation:
  LD50 - lethal dose 50% of test species, > 2000 mg/kg, rat. Material tested was a 75% aqueous solution of Tetrakis (hydroxymethyl) phosphonium sulfate.

Acute Respiratory Irritation:
  Toxicological Information and Interpretation:
  lung - lung irritation (qualitative), **. This material is not expected to cause significant irritation to the respiratory tract.

Acute Inhalation Toxicity:
The following data is for similar or related products.
  Toxicological Information and Interpretation:
  LC50 - lethal concentration 50% of test species, 0.59 mg/l/4 hr, rat. Material tested was a 75% aqueous solution of Tetrakis (hydroxymethyl) phosphonium sulfate.

Acute Oral Toxicity:
The following data is for similar or related products.
  Toxicological Information and Interpretation:
  LD50 - lethal dose 50% of test species, 575 mg/kg, rat. Material tested was a 75% aqueous solution of Tetrakis (hydroxymethyl) phosphonium sulfate.

Chronic Toxicity:
This product does not contain any substances that are considered by OSHA, NTP, IARC or ACGIH to be "probable" or "suspected" human carcinogens.

The following data is for the specified ingredients.

Toxicological Information and Interpretation - REPRODUCTIVE TOXICITY, rat. No impairment of fertility was observed in a two generation feeding study. Data for Tetrakis(hydroxymethyl)phosphonium sulfate. - CARCINOGENICITY, **. There was no evidence of carcinogenicity in F344/N rats and B6C3F1 mice (both sexes) dosed by gavage at 5 or 10 mg THPS/kg/day for 2 years. Ēref. NTP study report TR296, 1987|. Data for Tetrakis(hydroxymethyl)phosphonium sulfate. - MUTAGENICITY, **. Ames Test: Negative. Data for Tetrakis(hydroxymethyl)phosphonium sulfat. - MUTAGENICITY, **. Chinese hamester ovary cells (chromosomal aberrations): Positive. Data for Tetrakis(hydroxymethyl)phosphonium sulfate. - TERATOGENICITY, **. A developmental toxicity study in rabbits resulted in statistically significant developmental effects in offspring, principally including eye malformations, hydrocephaly and skeletal variations, at doses that also caused maternal (parental) bodyweight gain reduction. The No Observed Effect Level (NOEL) for development toxicity and maternal toxicity (rabbit) = 18 mg/kg/day. A developmental toxicity study in rats showed a statistically significant increase only in one skeletal variation (supernumary ribs), at doses that also caused maternal toxicity. The No Observed Effect Level for development toxicity (rat) = 30 mg/kg/day; No observed effect level for maternal toxicity (rat) = 15 mg/kg/day. Material tested was a 75% aqueous solution of Tetrakis (hydroxymethyl) phosphonium sulfate. Medical surveillance for over 30 years of employees in our manufacturing facility has shown no evidence of developmental toxicity from long-term exposure nor from exposure following an acute incident, for example, a major or minor spillage. - MUTAGENICITY, **. Dominant Lethal Assay Ērat| (in vivo): Negative. Data for active ingredient, Tetrakis(hydroxymethyl)phosphonium sulfate. - MUTAGENICITY, **. Mouse micronucleus (in vivo): Negative. Data for Tetrakis(hydroxymethyl)phosphonium sulfate. - MUTAGENICITY, **. Unscheduled DNA synthesis assay: Negative. Data for Tetrakis(hydroxymethyl)phosphonium sulfate. - SUB-CHRONIC EXPOSURE, 1 mg/kg/90 days, rat. Material tested was a 75% aqueous solution of Tetrakis (hydroxymethyl) phosphonium sulfate.


  12. ECOLOGICAL INFORMATION

Ecotoxicological Information:
Not expected to cause significant adverse environmental impact if product reaches waterways. The following data is for similar or related products.
  Ecotoxological Information and Interpretation:
  LC50 - lethal concentration 50% of test species, 19.4 mg/l/48 hr, Daphnia magna.
  LC50 - lethal concentration 50% of test species, 93 mg/l/96 hr, bluegill sunfish (Lepomis macrochirus).
  LC50 - lethal concentration 50% of test species, 119 mg/l/96 hr, rainbow trout (Oncorhynchus mykiss).
  LC50 - lethal concentration 50% of test species, 86 mg/l/96 hr, Juvenile Plaice.
  LC50 - lethal concentration 50% of test species, 340 mg/l/96 hr, Brown Shrimp.
  LC50 - ecotox Method for association with dry sediment weight., 2174 mg/kg/10 days, Corophium volutator. (dry sediment weight).
  LD50 - lethal dose 50% of test species, 311 mg/kg, Mallard duck (Anas platyrhynchos). Material tested was a 75% aqueous solution of Tetrakis (hydroxymethyl) phosphonium sulfate.

Chemical Fate Information:
Product is not expected to bioaccumulate. The following data is for similar or related product. THPS has been shown to degrade rapidly once diluted to sub-ppm concentrations and forms trishydroxymethyl phosphine oxide which is classified as non-toxic.


  13. DISPOSAL CONSIDERATIONS

Waste Disposal Method:
Chemical additions, processing or otherwise altering this material may make the waste management information presented in this MSDS incomplete, inaccurate or otherwise inappropriate. Please be advised that state and local requirements for waste disposal may be more restrictive or otherwise different from federal laws and regulations. Consult state and local regulations regarding the proper disposal of this material.

EPA Hazardous Waste - NO


  14. TRANSPORT INFORMATION

Transportation Status: IMPORTANT! Statements below provide additional data on listed DOT classification.
The listed Transportation Classification does not address regulatory variations due to changes in package size, mode of shipment or other regulatory descriptors.

US DOT:
Hazard Class..... 6.1
Shipping Name:
TOXIC LIQUID, ORGANIC, N.O.S.
Technical Shipping Name:
(TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULPHATE)
ID Number....... UN2810
Packing Group.... III
Labels........... TOXIC
Emergency Guide #.... 153

TDG:
Hazard Class..... 6.1
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Technical Shipping Name: (TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULPHATE)
ID Number....... UN2810
Packing Group.... III

IMO:
Hazard Class..... 6.1
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Technical Shipping Name: (TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULPHATE)
ID Number....... UN2810
Packing Group.... III

IATA:
Hazard Class..... 6.1
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Technical Shipping Name: (TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULPHATE)
ID Number....... UN2810
Packing Group.... III


  15. REGULATORY INFORMATION

Inventory Status
Inventory Status  
UNITED STATES (TSCA) Y  
CANADA (DSL) N  
EUROPE (EINECS/ELINCS) P  
AUSTRALIA (AICS) N  
JAPAN (MITI) N  
SOUTH KOREA (KECL) N  
 
Y = All ingredients are on the inventory.
E = All ingredients are on the inventory or exempt from listing.
P = One or more ingredients fall under the polymer exemption or are on the no longer polymer list. All other ingredients are on the inventory or exempt from listing.
N = Not determined or one or more ingredients are not on the inventory and are not exempt from listing.

FEDERAL REGULATIONS

Inventory Issues:
SARA Title III Hazard Classes: Fire Hazard - NO Reactive Hazard - NO Release of Pressure - NO Acute Health Hazard - YES Chronic Health Hazard - YES

SARA Title III Hazard Classes:
Fire Hazard - NO
Reactive Hazard - NO
Release of Pressure - NO
Acute Health Hazard - YES
Chronic Health Hazard - YES

STATE REGULATIONS:
This product contains the following components that are regulated under California Proposition 65:

Ingredient Name Cancer Reprod. No Sign. Risk Lvl (ug/day)
  List List California RPI
FORMALDEHYDE Y N 40 ND


  16. OTHER INFORMATION

National Fire Protection Association Hazard Ratings--NFPA(R):
3 Health Hazard Rating--Serious
0 Flammability Rating--Minimal
1 Instability Rating--Slight

National Paint & Coating Hazardous Materials Identification System--HMIS(R):
3 Health Hazard Rating--Serious
0 Flammability Rating--Minimal
1 Reactivity Rating--Slight

Reason for Revisions:
Change and/or addition made to Section 11.

Key Legend Information:
ACGIH - American Conference of Governmental Industrial Hygienists
OSHA - Occupational Safety and Health Administration
TLV - Threshold Limit Value
PEL - Permissable Exposure Limit
TWA - Time Weighted Average
STEL - Short Term Exposure Limit
NTP - National Toxicology Program
IARC - International Agency for Research on Cancer
ND - Not determined
RHODIA - Rhodia Established Exposure Limits

Disclaimer:
The information herein is given in good faith but no warranty, expressed or implied, is made.


  ** End of MSDS Document **